Sunset seen from UCSF Parnassus

Scientific Publications

Research Papers (Peer Reviewed)

1.         E2F-mediated Growth Regulation Requires Transcription Factor Cooperation. van Ginkel PR, Hsiao KM, Schjerven H, Farnham PJ. (1997), J Biol Chem, 272,18367-18374

2.         Mannuronan C-5-epimerases and their application for in vitro and in vivo design of new alginates useful in biotechnology. Ertesvåg H, Høidal HK, Schjerven H, Svanem BIG, Valla S. (1999), Metabolic Engineering, 1, 262-269

3.         Mechanism of IL-4-Mediated Up-Regulation of the Polymeric Ig Receptor: Role of STAT6 in Cell Type-Specific Delayed Transcriptional Response. Schjerven H, Brandtzaeg P, Johansen FE. (2000), J Immunol, 165: 3898-3906

4.         A Novel NF-kB/Rel Site in Intron 1 Cooperates with Proximal Promoter Elements to Mediate TNF-a-Induced Transcription of the Human Polymeric Ig Receptor. Schjerven H, Brandtzaeg P, Johansen FE. (2001) , J Immunol, 167: 6412-6420

5.         Hepatocyte NF-1 and STAT6 cooperate with additional DNA-binding factors to activate transcription of the human polymeric Ig receptor gene in response to IL-4. Schjerven H, Brandtzaeg P, Johansen FE. (2003), J Immunol, 170: 6048-6056

6.         Proinflammatory cytokines upregulate expression of calprotectin (L1 protein, MRP-8/MRP-14) in cultured human keratinocytes. Mork G, Schjerven H, Mangschau L, Soyland E, Brandtzaeg P. (2003), Br J Dermatol, 149: 484-491

7.         De Novo Synthesized RelB Mediates TNF-Induced Up-Regulation of the Human Polymeric Ig Receptor. Schjerven H, Tran TN, Brandtzaeg P, Johansen FE. (2004), J Immunol, 173:1849-1857

8.         Regulation of the polymeric Ig receptor by signalling through TLRs 3 and 4: linking innate and adaptive immune responses. Schneeman TA, Bruno MEC, Schjerven H, Johansen FE, Chady L, Kaetzel CS. (2005), J Immunol, 175: 376-384

9.         Regulation of B cell fate commitment and immunoglobulin V_H gene rearrangement by Ikaros. Reynaud D, Demarco I, Reddy K, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. (2008). Nat Immunol, 9(8): 927-936

10.       Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.  Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST. (2013) . Nat Immunol, 14(10): 1073-1083. 

11.        Restriction of IL-22- producing T Cell Responses and Differential Regulation of Regulatory T Cell Compartments by Zinc Finger Transcription Factor Ikaros. Heller J, Schjerven H*, Li S, Lee A, Qiu J, Chen ZE, Smale ST and Zhou L*. (2014). J Immunol., Vol 193 (8): 3934-46. PMID: 25194055   (*) Co-corresponding authors

12.       Identification of FOXM1 as therapeutic target in B cell lineage acute lymphoblastic leukemia. Buchner M, Park E, Geng H, Klemm L, Flach J, Passegue E, Schjerven H, Melnick A, Paietta E, Kopanja D, Raychaudhuri P, Muschen M.  (2015). Nature Communications. 6;6471. PMID: 25753524  

13.       Targeting casein kinase II restores Ikaros tumor suppressoractivity and demonstrates therapeutic efficacy in high-risk leukemia. Song C, Gowda C, Pan X, Ding Y, Tong Y, Tan BH, Wang H, Muthusami S, Ge Z, Sachdev M, Amin SG, Desai D, Gowda K, Gowda R, Robertson GP, Schjerven H, Muschen M, Payne KJ, Dovat S. Blood. 2015 Jul 28. pii: blood-2015-06-651505. [Epub ahead of print]. PMID: 26219304

14.       Regulation of gene expression dynamics during developmental transitions by the Ikaros transcription factor. Arenzana TL, Schjerven H, and Smale ST. (2015). Genes Dev. Sep 1;29(17):1801-16. PMID:26314708

15.        Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway. Li S, Heller JJ, Bostick JW, Lee A, Schjerven H, Kastner P, Chan S, Chen ZE, Zhou L. Immunity. 2016 Jul 19;45(1):185-97. PMID: 27438771

Reviews:

Norderhaug IN, Johansen FE, Schjerven H, Brandtzaeg P. (1999) Regulation of the formation and external transport of secretory immunoglobulins. Crit Rev Immunol 19:481-508

 

Chapters:

Johansen FE, Braathen R, Munthe E, Schjerven H and Brandtzaeg P. (2007) Regulation of the mucosal IgA system. In: Mucosal Immune Defense: Immunoglobulin A (Ed. Kaetzel CS), Kluwer Academic

 

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